There are different types of variants – they can be non-problem causing (benign), disease-causing (pathogenic) or of unknown significance. Variants can happen in genes and affect how the gene functions. Variants A variant is a change or alteration in a person’s DNA sequence. Over 20 different genes are known to cause SCID. Errors in the DNA that make up a gene are called variants and can lead to diseases. Chromosomes, and the genes on those chromosomes, are passed on from parent to child. People with SCID can have a change in one or more genes A segment of DNA that contains the instructions to make a specific protein (or part of a protein). They also cannot make antibodies to protect themselves. People with SCID are not able to fight off common infections. T cells are some of the cells that may be recruited during an immune response., and
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